Aging mothers, failing placentas? Association between maternal age and placental perfusion in a low-resource setting

Innocent Okafor Eze, Uchenna Ifeanyi Nwagha, Stephen Chijioke Eze, Asma’u Eleojo Abdul, Victor Cletus Igboezue and Rufai Muhammed

PLOS Global Public Health, 2026, vol. 6, issue 2, 1-8

Abstract: The prevalence of pregnancies among women of advanced maternal age (AMA, ≥ 35 years) is increasing globally. Age-related vascular changes may influence placental perfusion, but evidence isolating maternal age from major confounders remains limited, particularly in low-resource settings. The objective of the study was to examine the association between maternal age and placental vascular resistance, measured using the umbilical artery pulsatility index (UA-PI). This prospective cross-sectional comparative study was conducted at a tertiary military hospital in Lagos, Nigeria. One hundred pregnancies at term were stratified into younger maternal age (

Date: 2026
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pgph00:0005943

DOI: 10.1371/journal.pgph.0005943

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