Effectiveness of integrated care for older adults with depression and hypertension in rural China: A cluster randomized controlled trial

Shulin Chen, Yeates Conwell, Jiang Xue, Lydia Li, Tingjie Zhao, Wan Tang, Hillary Bogner and Hengjin Dong

PLOS Medicine, 2022, vol. 19, issue 10, 1-18

Abstract: Background: Effectiveness of integrated care management for common, comorbid physical and mental disorders has been insufficiently examined in low- and middle-income countries (LMICs). We tested hypotheses that older adults treated in rural Chinese primary care clinics with integrated care management of comorbid depression and hypertension (HTN) would show greater improvements in depression symptom severity and HTN control than those who received usual care. Methods and findings: The study, registered with ClinicalTrials.gov as Identifier NCT01938963, was a cluster randomized controlled trial with 12-month follow-up conducted from January 1, 2014 through September 30, 2018, with analyses conducted in 2020 to 2021. Participants were residents of 218 rural villages located in 10 randomly selected townships of Zhejiang Province, China. Each village hosts 1 primary care clinic that serves all residents. Ten townships, each containing approximately 20 villages, were randomly selected to deliver either the Chinese Older Adult Collaborations in Health (COACH) intervention or enhanced care-as-usual (eCAU) to eligible village clinic patients. The COACH intervention consisted of algorithm-driven treatment of depression and HTN by village primary care doctors supported by village lay workers with telephone consultation from centrally located psychiatrists. Participants included clinic patients aged ≥60 years with a diagnosis of HTN and clinically significant depressive symptoms (Patient Health Questionnaire-9 [PHQ-9] score ≥10). Of 2,899 eligible village residents, 2,365 (82%) agreed to participate. They had a mean age of 74.5 years, 67% were women, 55% had no schooling, 59% were married, and 20% lived alone. Conclusions: The COACH model of integrated care management resulted in greater improvement in both depression symptom severity and HTN control among older adult residents of rural Chinese villages who had both conditions than did eCAU. Trial registration: ClinicalTrials.gov Identifier NCT01938963 https://clinicaltrials.gov/ct2/show/NCT01938963. In a cluster randomized controlled trial, Shulin Chen and colleagues investigate whether integrated care management of depression and hypertension leads to greater improvements as compared to usual care in older adults attending rural Chinese primary care clinics.Why was this study done?: What did the researchers do and find?: What do these findings mean?:

Date: 2022
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pmed00:1004019

DOI: 10.1371/journal.pmed.1004019

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