Potential health impacts and costs of active case finding guided by Mycobacterium tuberculosis immunoreactivity survey results in Blantyre, Malawi: A mathematical modeling study

Sun Kim, Melike Hazal Can, Hannah M Rickman, Mphatso D Phiri, Marriott Nliwasa, Tisungane E Mwenyenkulu, Kuzani Mbendera, Stéphane Verguet, Marcia C Castro, Elizabeth L Corbett, Peter MacPherson, Ted Cohen and Nicolas A Menzies

PLOS Medicine, 2026, vol. 23, issue 10, 1-17

Abstract: Background: Active case finding (ACF) for tuberculosis (TB) can reduce transmission, yet efficient targeting requires high-quality surveillance data. We investigated the potential costs and impact of targeted ACF, guided by local estimates of the annual risk of TB infection (ARTI) derived from Mycobacterium tuberculosis (Mtb) immunoreactivity survey data in children aged

Date: 2026
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pmed00:1005272

DOI: 10.1371/journal.pmed.1005272

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