Epidemiological Assessment of Eight Rounds of Mass Drug Administration for Lymphatic Filariasis in India: Implications for Monitoring and Evaluation

Subramanian Swaminathan, Vanamail Perumal, Srividya Adinarayanan, Krishnamoorthy Kaliannagounder, Ravi Rengachari and Jambulingam Purushothaman

PLOS Neglected Tropical Diseases, 2012, vol. 6, issue 11, 1-13

Abstract: Background: Monitoring and evaluation guidelines of the programme to eliminate lymphatic filariasis require impact assessments in at least one sentinel and one spot-check site in each implementation unit (IU). Transmission assessment surveys (TAS) that assess antigenaemia (Ag) in children in IUs that have completed at least five rounds of mass drug administration (MDA) each with >65% coverage and with microfilaria (Mf) levels 70% of 50,363 population. The corresponding values for Ag were 2.3% and 17.3 Ag-units respectively. Ag-prevalence ranged from 0.7 to 0.9%, in children (2–10 years) and 2.7 to 3.0% in adults. Although the Mf-levels in the survey and the sentinel/spot check sites were 65% coverage, transmission assessment surveys (TAS) are carried out to decide on stopping further MDA. We used a mass blood survey in two primary health centres to assess the epidemiological situation after 8 rounds of MDA and evaluated the soundness of conclusions drawn from monitoring a few sites for initiating TAS. Mf-prevalence was 0.2%, both in the survey and monitoring sites, justifying the need for TAS, although data on MDA coverage was not available. The antigenaemia-prevalence in children born during the MDA period was 0.8%, well below the level (

Date: 2012
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pntd00:0001926

DOI: 10.1371/journal.pntd.0001926

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