Predicting Ebola Severity: A Clinical Prioritization Score for Ebola Virus Disease

Mary-Anne Hartley, Alyssa Young, Anh-Minh Tran, Harry Henry Okoni-Williams, Mohamed Suma, Brooke Mancuso, Ahmed Al-Dikhari and Mohamed Faouzi

PLOS Neglected Tropical Diseases, 2017, vol. 11, issue 2, 1-20

Abstract: Background: Despite the notoriety of Ebola virus disease (EVD) as one of the world’s most deadly infections, EVD has a wide range of outcomes, where asymptomatic infection may be almost as common as fatality. With increasingly sensitive EVD diagnosis, there is a need for more accurate prognostic tools that objectively stratify clinical severity to better allocate limited resources and identify those most in need of intensive treatment. Methods/Principal Findings: This retrospective cohort study analyses the clinical characteristics of 158 EVD(+) patients at the GOAL-Mathaska Ebola Treatment Centre, Sierra Leone. The prognostic potential of each characteristic was assessed and incorporated into a statistically weighted disease score. The mortality rate among EVD(+) patients was 60.8% and highest in those aged 25 years (p

Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pntd00:0005265

DOI: 10.1371/journal.pntd.0005265

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