Socio-economic and environmental factors associated with high lymphatic filariasis morbidity prevalence distribution in Bangladesh

Tijana Williams, Mohammad Jahirul Karim, Shihab Uddin, Sharmin Jahan, Sultan Mahmood Asm, Shaun P Forbes, Anna Hooper, Mark J Taylor and Louise A Kelly-Hope

PLOS Neglected Tropical Diseases, 2023, vol. 17, issue 7, 1-16

Abstract: Background: Lymphatic filariasis (LF) is a vector-borne parasitic disease which affects 70 million people worldwide and causes life-long disabilities. In Bangladesh, there are an estimated 44,000 people suffering from clinical conditions such as lymphoedema and hydrocoele, with the greatest burden in the northern Rangpur division. To better understand the factors associated with this distribution, this study examined socio-economic and environmental factors at division, district, and sub-district levels. Methodology: A retrospective ecological study was conducted using key socio-economic (nutrition, poverty, employment, education, house infrastructure) and environmental (temperature, precipitation, elevation, waterway) factors. Characteristics at division level were summarised. Bivariate analysis using Spearman’s rank correlation coefficient was conducted at district and sub-district levels, and negative binomial regression analyses were conducted across high endemic sub-districts (n = 132). Maps were produced of high endemic sub-districts to visually illustrate the socio-economic and environmental factors found to be significant. Results: The highest proportion of rural population (86.8%), poverty (42.0%), tube well water (85.4%), and primary employment in agriculture (67.7%) was found in Rangpur division. Conclusions: This study highlights the value of using available data to identify key drivers associated with high LF morbidity prevalence, which may help national LF programmes better identify populations at risk and implement timely and targeted public health messages and intervention strategies. Author summary: Lymphatic Filariasis (LF) is particularly associated with poverty and living in a rural area, where disease transmitting mosquito vectors thrive. To better understand the socio-economic and environmental factors associated with the LF morbidity prevalence distribution in Bangladesh, this study examined publicly available data and used descriptive, statistical, and mapping methods to highlight key associations. Results found that high risk populations were those living in rural areas, employed in agriculture, with high levels of poverty, and houses without electricity or toilets, and where temperatures in the rainy season were lower than other regions of the country. These findings will help to inform public health messages and implement interventions for people affected by LF morbidity, but also to help reduce any current and future risk of transmission. This will support progress to achieving WHO elimination targets, leading to a future free of suffering for people affected by LF associated morbidity.

Date: 2023
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pntd00:0011457

DOI: 10.1371/journal.pntd.0011457

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