The Impact of National Institutes of Health Funding on U.S. Cardiovascular Disease Research
Radmila Lyubarova,
Brandon K Itagaki and
Michael W Itagaki
PLOS ONE, 2009, vol. 4, issue 7, 1-8
Abstract:
Background: Intense interest surrounds the recent expansion of US National Institutes of Health (NIH) budgets as part of economic stimulus legislation. However, the relationship between NIH funding and cardiovascular disease research is poorly understood, making the likely impact of this policy change unclear. Methods: The National Library of Medicine's PubMed database was searched for articles published from 1996 to 2006, originating from U.S. institutions, and containing the phrases “cardiolog,” “cardiovascular,” or “cardiac,” in the first author's department. Research methodology, journal of publication, journal impact factor, and receipt of NIH funding were recorded. Differences in means and trends were tested with t-tests and linear regression, respectively, with P≤0.05 for significance. Results: Of 117,643 world cardiovascular articles, 36,684 (31.2%) originated from the U.S., of which 10,293 (28.1%) received NIH funding. The NIH funded 40.1% of U.S. basic science articles, 20.3% of overall clinical trials, 18.1% of randomized-controlled, and 12.2% of multicenter clinical trials. NIH-funded and total articles grew significantly (65 articles/year, P
Date: 2009
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0006425
DOI: 10.1371/journal.pone.0006425
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