Neighborhood Socioeconomic Deprivation and Mortality: NIH-AARP Diet and Health Study

Jacqueline M Major, Chyke A Doubeni, Neal D Freedman, Yikyung Park, Min Lian, Albert R Hollenbeck, Arthur Schatzkin, Barry I Graubard and Rashmi Sinha

PLOS ONE, 2010, vol. 5, issue 11, 1-6

Abstract: Purpose: Residing in deprived areas may increase risk of mortality beyond that explained by a person's own SES-related factors and lifestyle. The aim of this study was to examine the relation between neighborhood socioeconomic deprivation and all-cause, cancer- and cardiovascular disease (CVD)-specific mortality for men and women after accounting for education and other important person-level risk factors. Methods: In the longitudinal NIH-AARP Study, we analyzed data from healthy participants, ages 50–71 years at study baseline (1995–1996). Deaths (n = 33831) were identified through December 2005. Information on census tracts was obtained from the 2000 US Census. Cox models estimated hazard ratios (HRs) and 95% confidence intervals (CIs) for quintiles of neighborhood deprivation. Results: Participants in the highest quintile of deprivation had elevated risks for overall mortality (HRmen = 1.17, 95% CI: 1.10, 1.24; HRwomen = 1.13, 95% CI: 1.05, 1.22) and marginally increased risk for cancer deaths (HRmen = 1.09, 95% CI: 1.00, 1.20; HRwomen = 1.09, 95% CI: 0.99, 1.22). CVD mortality associations appeared stronger in men (HR = 1.33, 95% CI: 1.19, 1.49) than women (HR = 1.18, 95% CI: 1.01, 1.38). There was no evidence of an effect modification by education. Conclusion: Higher neighborhood deprivation was associated with modest increases in all-cause, cancer- and CVD-mortality after accounting for many established risk factors.

Date: 2010
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0015538

DOI: 10.1371/journal.pone.0015538

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