LINGO1 Variants in the French-Canadian Population

Cynthia V Bourassa, Jean-Baptiste Rivière, Patrick A Dion, Geneviève Bernard, Sabrina Diab, Michel Panisset, Sylvain Chouinard, Nicolas Dupré, Hélène Fournier, John Raelson, Majid Belouchi and Guy A Rouleau

PLOS ONE, 2011, vol. 6, issue 1, 1-3

Abstract: Essential tremor (ET) is a complex genetic disorder for which no causative gene has been found. Recently, a genome-wide association study reported that two variants in the LINGO1 locus were associated to this disease. The aim of the present study was to test if this specific association could be replicated using a French-Canadian cohort of 259 ET patients and 479 ethnically matched controls. Our genotyping results lead us to conclude that no association exists between the key variant rs9652490 and ET (Pcorr = 1.00).

Date: 2011
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0016254

DOI: 10.1371/journal.pone.0016254

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