The SOS Pilot Study: A RCT of Routine Oxygen Supplementation Early after Acute Stroke—Effect on Recovery of Neurological Function at One Week

Christine Roffe, Khalid Ali, Anushka Warusevitane, Sheila Sills, Sarah Pountain, Martin Allen, John Hodsoll, Frank Lally, Peter Jones and Peter Crome

PLOS ONE, 2011, vol. 6, issue 5, 1-9

Abstract: Methods: Patients with a clinical diagnosis of acute stroke were recruited within 24 h of hospital admission between October 2004 and April 2008. Participants were randomized to oxygen via nasal cannulae (72 h) or control (room air, oxygen given only if clinically indicated). Clinical outcomes were assessed by research team members at 1 week. Baseline data for oxygen (n = 148) and control (n = 141) did not differ between groups. Results: The median (interquartile range) National Institutes of Health Stroke Scale (NIHSS) score for the groups at baseline was 6 (7) and 5 (7) respectively. The median Nocturnal Oxygen Saturation during treatment was 1.4% (0.3) higher in the oxygen than in the control group (p

Date: 2011
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0019113

DOI: 10.1371/journal.pone.0019113

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