Incidence of Influenza in Healthy Adults and Healthcare Workers: A Systematic Review and Meta-Analysis

Stefan P Kuster, Prakesh S Shah, Brenda L Coleman, Po-Po Lam, Agnes Tong, Anne Wormsbecker and Allison McGeer

PLOS ONE, 2011, vol. 6, issue 10, 1-9

Abstract: Background: Working in healthcare is often considered a risk factor for influenza; however, this risk has not been quantified. We aimed to systematically review evidence describing the annual incidence of influenza among healthy adults and healthcare workers (HCWs). Methods and Findings: We searched OVID MEDLINE (1950 to 2010), EMBASE (1947 to 2010) and reference lists of identified articles. Observational studies or randomized trials reporting full season or annual influenza infection rates for healthy, working age adult subjects and HCWs were included. Influenza infection was defined as a four-fold rise in antibody titer, or positive viral culture or polymerase chain reaction. Conclusions: Compared to adults working in non-healthcare settings, HCWs are at significantly higher risk of influenza.

Date: 2011
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0026239

DOI: 10.1371/journal.pone.0026239

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