Identification of Cancer Cell-Line Origins Using Fluorescence Image-Based Phenomic Screening
Jun-Seok Lee,
Yun Kyung Kim,
Han Jo Kim,
Siti Hajar,
Yee Ling Tan,
Nam-Young Kang,
Shin Hui Ng,
Chang No Yoon and
Young-Tae Chang
PLOS ONE, 2012, vol. 7, issue 2, 1-8
Abstract:
Universal phenotyping techniques that can discriminate among various states of biological systems have great potential. We applied 557 fluorescent library compounds to NCI's 60 human cancer cell-lines (NCI-60) to generate a systematic fluorescence phenotypic profiling data. By the kinetic fluorescence intensity analysis, we successfully discriminated the organ origin of all the 60 cell-lines.
Date: 2012
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0032096
DOI: 10.1371/journal.pone.0032096
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