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Identification of Cancer Cell-Line Origins Using Fluorescence Image-Based Phenomic Screening

Jun-Seok Lee, Yun Kyung Kim, Han Jo Kim, Siti Hajar, Yee Ling Tan, Nam-Young Kang, Shin Hui Ng, Chang No Yoon and Young-Tae Chang

PLOS ONE, 2012, vol. 7, issue 2, 1-8

Abstract: Universal phenotyping techniques that can discriminate among various states of biological systems have great potential. We applied 557 fluorescent library compounds to NCI's 60 human cancer cell-lines (NCI-60) to generate a systematic fluorescence phenotypic profiling data. By the kinetic fluorescence intensity analysis, we successfully discriminated the organ origin of all the 60 cell-lines.

Date: 2012
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0032096

DOI: 10.1371/journal.pone.0032096

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