Integrating Prevention of Mother-to-Child HIV Transmission Programs to Improve Uptake: A Systematic Review

Lorainne Tudor Car, Michelle H M M T Van Velthoven, Serena Brusamento, Hoda Elmoniry, Josip Car, Azeem Majeed, Peter Tugwell, Vivian Welch, Ana Marusic and Rifat Atun

PLOS ONE, 2012, vol. 7, issue 4, 1-8

Abstract: Background: We performed a systematic review to assess the effect of integrated perinatal prevention of mother-to-child transmission of HIV interventions compared to non- or partially integrated services on the uptake in low- and middle-income countries. Methods: We searched for experimental, quasi-experimental and controlled observational studies in any language from 21 databases and grey literature sources. Results: Out of 28 654 citations retrieved, five studies met our inclusion criteria. A cluster randomized controlled trial reported higher probability of nevirapine uptake at the labor wards implementing HIV testing and structured nevirapine adherence assessment (RRR 1.37, bootstrapped 95% CI, 1.04–1.77). A stepped wedge design study showed marked improvement in antiretroviral therapy (ART) enrolment (44.4% versus 25.3%, p

Date: 2012
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0035268

DOI: 10.1371/journal.pone.0035268

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