Reliability and Diagnostic Performance of CT Imaging Criteria in the Diagnosis of Tuberculous Meningitis

Hugo Botha, Christelle Ackerman, Sally Candy, Jonathan A Carr, Stephanie Griffith-Richards and Kathleen J Bateman

PLOS ONE, 2012, vol. 7, issue 6, 1-8

Abstract: Introduction: Abnormalities on CT imaging may contribute to the diagnosis of tuberculous meningitis (TBM). Recently, an expert consensus case definition (CCD) and set of imaging criteria for diagnosing basal meningeal enhancement (BME) have been proposed. This study aimed to evaluate the sensitivity, specificity and reliability of these in a prospective cohort of adult meningitis patients. Methods: Initial diagnoses were based on the CCD, classifying patients into: ‘Definite TBM’ (microbiological confirmation), ‘Probable TBM’ (diagnostic score ≥10), ‘Possible TBM’ (diagnostic score 6–9), ‘Not TBM’ (confirmation of an alternative diagnosis) or ‘Uncertain’ (diagnostic score of

Date: 2012
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0038982

DOI: 10.1371/journal.pone.0038982

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