Bias in Amputation Research; Impact of Subjects Missed from a Prospective Study

Lauren V Fortington, Jan H B Geertzen, Joline C Bosmans and Pieter U Dijkstra

PLOS ONE, 2012, vol. 7, issue 8, 1-6

Abstract: For research findings to be generalized, a sample must be representative of the actual population of interest. Lower limb amputation is most frequently performed in older patients with vascular disease, a population that is often under-represented in research. The aim of this study was to explore the impact of selection bias by comparing characteristics from a sample included in a prospective study of phantom pain with the actual population who underwent amputation. Only 27% of all potential patients were referred during the first year of the prospective study. The referred patients were 8 years younger (p

Date: 2012
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0043629

DOI: 10.1371/journal.pone.0043629

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