Epidemiology of Functional Diarrhea and Comparison with Diarrhea-Predominant Irritable Bowel Syndrome: A Population-Based Survey in China

Yan-Fang Zhao, Xiao-Jing Guo, Zhan-Sai Zhang, Xiu-Qiang Ma, Rui Wang, Xiao-Yan Yan and Jia He

PLOS ONE, 2012, vol. 7, issue 8, 1-7

Abstract: Background: The epidemiology of functional diarrhea and its impacts on Chinese remain unclear, and there are no data on the comparative epidemiology of functional diarrhea and diarrhea-predominant irritable bowel syndrome (IBS-D). This study was to explore the epidemiology of functional diarrhea and its impacts, and to identify its distinction from IBS-D. Methods and Findings: A cross-sectional survey was conducted in 16078 respondents, who were interviewed under a randomized stratified multi-stage sampling design in five cities of China. All respondents completed the modified Rome II questionnaire, and the 36-item Short Form health survey (SF-36) was used for assessing health-related quality of life in 20% of the sample. Overall, 248 respondents (1.54%) had functional diarrhea and 277 (1.72%) had IBS-D. Functional diarrhea was positively associated with increasing age and body mass index (trend test P

Date: 2012
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0043749

DOI: 10.1371/journal.pone.0043749

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