Development and Validation of a Vitamin D Status Prediction Model in Danish Pregnant Women: A Study of the Danish National Birth Cohort

Camilla Bjørn Jensen, Andrew L Thorne-Lyman, Linda Vadgård Hansen, Marin Strøm, Nina Odgaard Nielsen, Arieh Cohen and Sjurdur Frodi Olsen

PLOS ONE, 2013, vol. 8, issue 1, 1-8

Abstract: Vitamin D has been hypothesized to reduce risk of pregnancy complications such as preeclampsia, gestational diabetes mellitus, and preterm delivery. However, many of these outcomes are rare and require a large sample size to study, representing a challenge for cohorts with a limited number of preserved samples. The aims of this study were to (1) identify predictors of serum 25-hydroxy-vitamin D (25(OH)D) among pregnant women in a subsample (N = 1494) of the Danish National Birth Cohort (DNBC) and (2) develop and validate a score predicting 25(OH)D-status in order to explore associations between vitamin D and maternal and offspring health outcomes in the DNBC. In our study sample, 42.3% of the population had deficient levels of vitamin D (

Date: 2013
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0053059

DOI: 10.1371/journal.pone.0053059

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