Obesity and Risk of Hip Fracture in Adults: A Meta-Analysis of Prospective Cohort Studies

Xianye Tang, Gang Liu, Jian Kang, Yang Hou, Fungui Jiang, Wen Yuan and Jiangang Shi

PLOS ONE, 2013, vol. 8, issue 4, 1-7

Abstract: Background: Many observational studies assessed the association between obesity and risk of hip fracture in adults, but reported controversial results. Our goal was to evaluate the association between obesity and risk of hip fracture in adults by conducting a meta-analysis of prospective cohort studies. Methods: Three databases, PubMed, Embase and Web of Science, were searched through May 2012 to identify eligible cohort studies. Either a fixed- or a random-effects model was used to calculate the pooled relative risk (RR) with its 95% confidence interval (95%CI). Results: Fifteen prospective cohort studies involving a total 3,126,313 participants were finally included into this meta-analysis. Overall, adults with obesity compared with the normal weight group had a significantly decreased risk of hip fracture (RR: 0.66, 95% CI 0.57 to 0.77, P

Date: 2013
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0055077

DOI: 10.1371/journal.pone.0055077

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