Measurement of Variceal Pressure with a Computerized Endoscopic Manometry: Validation and Effect of Propranolol Therapy in Cirrhotic Patients

Kong De-Run, Chao Zhang, Lei Zhang, Jing-Guang Wang, Zhuang Xiong, Pan Li and Jian-Ming Xu

PLOS ONE, 2013, vol. 8, issue 2, 1-10

Abstract: Background and Purpose: Recently, we invented a computerized endoscopic balloon manometry (CEBM) to measure variceal pressure (VP) in cirrhotic patient. The purpose of this study was to evaluate the reliability and feasibility of this method, and whether this technique provided further information to pharmacological therapy. Patients and Methods: VP measurements were performed in 83 cirrhotic patients and compared with HVPG as well as endoscopic bleeding risk parameters. Furthermore, VP was assessed before and during propranolol therapy in 30 patients without previous bleeding. Results: VP measurements were successful in 96% (83/86) of all patients. Of the 83 patients, the VP correlated closely with the HVPG (P

Date: 2013
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0056332

DOI: 10.1371/journal.pone.0056332

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