NT-proBNP, C-Reactive Protein and Soluble uPAR in a Bi-Ethnic Male Population: The SAfrEIC Study

Ruan Kruger, Rudolph Schutte, Hugo W Huisman, Peter Hindersson, Michael H Olsen, Jesper Eugen-Olsen and Aletta E Schutte

PLOS ONE, 2013, vol. 8, issue 3, 1-6

Abstract: Objective and design: This cross-sectional study aimed to investigate associations between a marker of cardiac strain, the N-terminal prohormone B-type natriuretic peptide (NT-proBNP), and inflammation as reflected by either a conventional or novel inflammatory marker in a bi-ethnic South African cohort. Methods and subjects: We measured NT-proBNP, C-reactive protein (CRP) and plasma-soluble urokinase plasminogen activator receptor (suPAR) levels along with conventional biomarkers in black (n = 117) and white (n = 116) men. Results: NT-proBNP, CRP and suPAR levels were higher in black compared to white men. NT-proBNP was significantly associated with both CRP (r = 0.38; p = 0.001) and suPAR (r = 0.42; p

Date: 2013
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0058506

DOI: 10.1371/journal.pone.0058506

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