Association of TCF7L2 Gene Polymorphisms with T2DM in the Population of Hyderabad, India

Kommoju Uma Jyothi, Maruda Jayaraj, Kadarkarai Samy Subburaj, Kotla Jaya Prasad, Irgam Kumuda, Velaga Lakshmi and Battini Mohan Reddy

PLOS ONE, 2013, vol. 8, issue 4, 1-7

Abstract: We attempt to evaluate the nature of association of TCF7L2 gene variants with T2DM, for the first time in the population of Hyderabad, which is considered to be diabetic capital of India. It is a case-control study of the three SNPs of TCF7L2, rs7903146, rs12255372 and rs11196205, genotyped on Sequenom Massarray platform, in a sample of 758 patients and 621 controls. The risk allele frequency of the three SNPs was found to be significantly higher in the T2DM cases than controls, implicating susceptibility for diabetes (p

Date: 2013
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0060212

DOI: 10.1371/journal.pone.0060212

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