Cobalamin Analogues in Humans: A Study on Maternal and Cord Blood

Tore Forsingdal Hardlei, Rima Obeid, Wolfgang Herrmann and Ebba Nexo

PLOS ONE, 2013, vol. 8, issue 4, 1-4

Abstract: Background: Haptocorrin (HC) carries cobalamin analogues (CorA), but whether CorA are produced in the body is unknown. All cobalamins (Cbl) to the foetus are delivered by the Cbl-specific protein transcobalamin (TC), and therefore analysis of cord serum for CorA may help to clarify the origin of CorA. Methods: HC-CorA were quantified in paired samples of cord serum from newborns and serum from mothers (n = 69). Results: The CorA-concentration was higher in cord serum (median = 380, range: 41–780 pmol/L) than in serum from the mothers (median = 160, range: 64–330 pmol/L), (p

Date: 2013
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0061194

DOI: 10.1371/journal.pone.0061194

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