Association of Weight-Adjusted Body Fat and Fat Distribution with Bone Mineral Density in Middle-Aged Chinese Adults: A Cross-Sectional Study

Yan-hua Liu, Ying Xu, Ya-bin Wen, Ke Guan, Wen-hua Ling, Li-ping He, Yi-xiang Su and Yu-ming Chen

PLOS ONE, 2013, vol. 8, issue 5, 1-9

Abstract: Background: Although it is well established that a higher body weight is protective against osteoporosis, the effects of body fat and fat distribution on bone mineral density (BMD) after adjustment for body weight remains uncertain. Objective: To examine the relationship between body fat and fat distribution and BMD beyond its weight-bearing effect in middle-aged Chinese adults. Method: The study had a community-based cross-sectional design and involved 1,767 women and 698 men aged 50–75 years. The BMD of the lumbar spine, total hip, and whole body, and the fat mass (FM) and percentage fat mass (%FM) of the total body and segments of the body were measured by dual-energy X-ray absorptiometry. General information on the participants was collected using structured questionnaire interviews. Result: After adjusting for potential confounders, an analysis of covariance showed the weight-adjusted (WA-) total FM (or %FM) to be negatively associated with BMD in all of the studied sites (P

Date: 2013
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0063339

DOI: 10.1371/journal.pone.0063339

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