Plasmidome-Analysis of ESBL-Producing Escherichia coli Using Conventional Typing and High-Throughput Sequencing

Alma Brolund, Oscar Franzén, Öjar Melefors, Karin Tegmark-Wisell and Linus Sandegren

PLOS ONE, 2013, vol. 8, issue 6, 1-11

Abstract: Infections caused by Extended spectrum β-lactamase (ESBL)-producing E. coli are an emerging global problem, threatening the effectiveness of the extensively used β-lactam antibiotics. ESBL dissemination is facilitated by plasmids, transposons, and other mobile elements. We have characterized the plasmid content of ESBL-producing E. coli from human urinary tract infections. Ten diverse isolates were selected; they had unrelated pulsed-field gel electrophoresis (PFGE) types (

Date: 2013
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0065793

DOI: 10.1371/journal.pone.0065793

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