Prediabetes Is Associated with an Increased Risk of Testosterone Deficiency, Independent of Obesity and Metabolic Syndrome

Chen-Hsun Ho, Hong-Jeng Yu, Chih-Yuan Wang, Fu-Shan Jaw, Ju-Ton Hsieh, Wan-Chung Liao, Yeong-Shiau Pu and Shih-Ping Liu

PLOS ONE, 2013, vol. 8, issue 9, 1-

Abstract: Objective: The association between type 2 diabetes and low testosterone has been well recognized. However, testosterone levels in men with prediabetes have been rarely reported. We aimed to investigate whether prediabetes was associated with an increased risk of testosterone deficiency. Methods: This study included 1,306 men whose sex hormones was measured during a medical examination. Serum total testosterone and sex hormone-binding globulin were measured; free and bioavailable testosterone concentrations were calculated by Vermeulen’s formula. Prediabetes was defined by impaired fasting glucose (IFG), impaired postprandial glucose (IPG), or glycated hemoglobin (HbA1c) 5.7%-6.4%. Logistic regression was performed to obtain the odds ratios (OR) for subnormal total testosterone (

Date: 2013
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0074173

DOI: 10.1371/journal.pone.0074173

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