Longitudinal Lung Function Growth of Mexican Children Compared with International Studies

David Martínez-Briseño, Rosario Fernández-Plata, Laura Gochicoa-Rangel, Luis Torre-Bouscoulet, Rosalba Rojas-Martínez, Laura Mendoza, Cecilia García-Sancho and Rogelio Pérez-Padilla

PLOS ONE, 2013, vol. 8, issue 10, 1-

Abstract: Introduction: Our aim was to compare the longitudinal lung function growth of Mexican children and adolescents with the collated spirometric reference proposed for international use and with that of Mexican-Americans from the National Health State Examination Survey III (NHANES) III study. Materials and Methods: A cohort of Mexican children in third year of primary school was followed with spirometry twice a year through secondary school. Multilevel mixed-effects lineal models separated by gender were fit for the spirometric variables of 2,641 respiratory-healthy Mexican children expressed as Z-scores of tested reference equations. Impact of adjustment by sitting height on differences with Mexican-American children was observed in a subsample of 1,987 children. Results: At same gender, age, and height, Mexican children had increasingly higher forced expiratory volume in 1 s (FEV1) and Forced vital capacity (FVC) than the children from the collated reference study (mean Z-score, 0.68 for FEV1 and 0.51 for FVC) and than Mexican-American children (Z-score, 0.23 for FEV1 and 0.21 for FVC) respectively. Differences with Mexican-Americans were not reduced by adjusting by sitting height. Conclusions: For reasons that remain unclear, the gender-, age-, and height-adjusted lung function of children from Mexico City is higher than that reported by several international studies.

Date: 2013
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0077403

DOI: 10.1371/journal.pone.0077403

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