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Helicobacter pylori Infection Is Associated with the Presence of Thyroid Nodules in the Euthyroid Population

Zhe Shen, Yu’e Qin, Yi Liu, Yi Lu, Stefan Munker, Lihua Chen, Chaohui Yu, Peng Chen and Youming Li

PLOS ONE, 2013, vol. 8, issue 11, 1-

Abstract: Helicobacter pylori infection is associated with extragastric diseases. The thyroid may be one of the targets of chronic inflammation. Here, we sought to investigate whether H. pylori infections were associated with the presence of thyroid nodules. A total of 988 euthyroid subjects from China were included in this cross-sectional study. Four hundred thirty-five (44.0%) subjects were diagnosed as having thyroid nodules, and 486 (49.2%) were diagnosed with H. pylori infections. The thyroid nodules group had a higher proportion of H. pylori infections than the control group (P = 0.002). Free thyroxine (FT4) levels were lower and the prevalence of thyroid nodules was higher in patients with H. pylori infection compared to those without infection, even after adjustment for age, gender, and body mass index (BMI; all P

Date: 2013
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0080042

DOI: 10.1371/journal.pone.0080042

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