Glycated Hemoglobin Independently Predicts Stroke Recurrence within One Year after Acute First-Ever Non-Cardioembolic Strokes Onset in A Chinese Cohort Study

Shuolin Wu, Yuzhi Shi, Chunxue Wang, Qian Jia, Ning Zhang, Xingquan Zhao, Gaifen Liu, Yilong Wang, Liping Liu, Yongjun Wang and On Behalf of the Investigators for the Survey on Abnormal Glucose Regulation in Patients With Acute Stroke Across China (ACROSS-China)

PLOS ONE, 2013, vol. 8, issue 11, 1-

Abstract: Objective: Hyperglycemia is related to stroke. Glycated hemoglobin (HbA1c) can reflect pre-stroke glycaemia status. However, the information on the direct association between HbA1c and recurrence after non-cardioembolic acute ischemic strokes is rare and there is no consistent conclusion. Methods: The ACROSS-China database comprised of 2186 consecutive first-ever acute ischemic stroke patients with baseline HbA1c values. After excluding patients who died from non-stroke recurrence and patients lost to follow up, 1817 and 1540 were eligible for 3-month and 1-year analyses, respectively. Multivariate Cox regression was performed to evaluate the associations between HbA1c and 3-month and 1-year stroke recurrence. Results: The HbA1c values at admission were divided into 4 levels by quartiles: Q1 (

Date: 2013
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0080690

DOI: 10.1371/journal.pone.0080690

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