Serum Interleukin-18 Levels Are Associated with Physical Activity in Japanese Men

Kanae Oda, Nobuyuki Miyatake, Noriko Sakano, Takeshi Saito, Motohiko Miyachi, Izumi Tabata and Takeyuki Numata

PLOS ONE, 2013, vol. 8, issue 12, 1-5

Abstract: Objective: To investigate the link between serum interleukin-18 (IL-18) levels and physical activity in Japanese men. Methods: A total of 81 men (45.7±17.6 years old) was enrolled in this cross-sectional investigation study. We assessed anthropometric and body composition parameters. Serum IL-18 levels, physical activity by uniaxial accelerometers, peak oxygen uptake and metabolic risk parameters were also evaluated. Results: Serum IL-18 levels were 179.4±84.7 pg/mL. Physical activity evaluated by Σ[metabolic equivalents × h per week (METs⋅h/w)]was significantly and negatively correlated with serum IL-18 levels (r = −0.252, p = 0.0235). These associations remained even after adjusting for age, peak oxygen uptake and other confounding factors. Conclusion: Serum IL-18 levels were closely associated with physical activity independent of peak oxygen uptake in Japanese men.

Date: 2013
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0081497

DOI: 10.1371/journal.pone.0081497

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