Impact of Uncertainties in Exposure Assessment on Estimates of Thyroid Cancer Risk among Ukrainian Children and Adolescents Exposed from the Chernobyl Accident

Mark P Little, Alexander G Kukush, Sergii V Masiuk, Sergiy Shklyar, Raymond J Carroll, Jay H Lubin, Deukwoo Kwon, Alina V Brenner, Mykola D Tronko, Kiyohiko Mabuchi, Tetiana I Bogdanova, Maureen Hatch, Lydia B Zablotska, Valeriy P Tereshchenko, Evgenia Ostroumova, André C Bouville, Vladimir Drozdovitch, Mykola I Chepurny, Lina N Kovgan, Steven L Simon, Victor M Shpak and Ilya A Likhtarev

PLOS ONE, 2014, vol. 9, issue 1, 1-9

Abstract: The 1986 accident at the Chernobyl nuclear power plant remains the most serious nuclear accident in history, and excess thyroid cancers, particularly among those exposed to releases of iodine-131 remain the best-documented sequelae. Failure to take dose-measurement error into account can lead to bias in assessments of dose-response slope. Although risks in the Ukrainian-US thyroid screening study have been previously evaluated, errors in dose assessments have not been addressed hitherto. Dose-response patterns were examined in a thyroid screening prevalence cohort of 13,127 persons aged

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0085723

DOI: 10.1371/journal.pone.0085723

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