Chloroquine Is Grossly Under Dosed in Young Children with Malaria: Implications for Drug Resistance

Johan Ursing, Staffan Eksborg, Lars Rombo, Yngve Bergqvist, Daniel Blessborn, Amabelia Rodrigues and Poul-Erik Kofoed

PLOS ONE, 2014, vol. 9, issue 1, 1-6

Abstract: Background: Plasmodium falciparum malaria is treated with 25 mg/kg of chloroquine (CQ) irrespective of age. Theoretically, CQ should be dosed according to body surface area (BSA). The effect of dosing CQ according to BSA has not been determined but doubling the dose per kg doubled the efficacy of CQ in children aged

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0086801

DOI: 10.1371/journal.pone.0086801

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