Sleep-Wake Cycle in Young and Older Persons with a Lifetime History of Mood Disorders

Rébecca Robillard, Sharon L Naismith, Kristie Leigh Smith, Naomi L Rogers, Django White, Zoe Terpening, Tony K C Ip, Daniel F Hermens, Bradley Whitwell, Elizabeth M Scott and Ian B Hickie

PLOS ONE, 2014, vol. 9, issue 2, 1-8

Abstract: Considering the marked changes in sleep and circadian rhythms across the lifespan, age may contribute to the heterogeneity in sleep-wake profiles linked to mood disorders. This study aimed to investigate the contributions of age and depression severity to sleep-wake disturbances. The Hamilton Depression Rating Scale (HDRS) was administered to assess current symptoms severity in 238 persons with a history of a mood disorder between 12 and 90 years of age (y.o.). Actigraphy was recorded over five to 22 days. Regression analyses and analyses of variance [age (12–19 y.o., 20–39 y.o., 40–59 y.o., and ≥60 y.o.) by depression severity (HDRS

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0087763

DOI: 10.1371/journal.pone.0087763

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