Impaired Dynamic Cerebral Autoregulation and Cerebrovascular Reactivity in Middle Cerebral Artery Stenosis

Jie Chen, Jia Liu, Wei-Hai Xu, Ren Xu, Bo Hou, Li-Ying Cui and Shan Gao

PLOS ONE, 2014, vol. 9, issue 2, 1-6

Abstract: Purpose: We sought to investigate the capacity of cerebral autoregulation and cerebrovascular reactivity (CVR) in patients with middle cerebral artery (MCA) stenosis. Methods: Twenty-one patients with MCA stenosis diagnosed by magnetic resonance angiography and 15 healthy controls were enrolled. Cerebral autoregulation was assessed by autoregulatory parameters (rate of recovery/phase/gain) derived from transfer function from spontaneous oscillations of cerebral blood flow velocity and blood pressure. CVR was tested by a rebreathing maneuver. Results: Rate of recovery, phase and CVR estimated from moderate MCA stenosis (rate of recovery = 17.76±8.21%/s, phase = 26.93±15.67°, and CVR = 1.53±0.84%/mmHg, respectively) were significantly different (p

Date: 2014
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088232 (text/html)
https://journals.plos.org/plosone/article/file?id= ... 88232&type=printable (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0088232

DOI: 10.1371/journal.pone.0088232

Access Statistics for this article

More articles in PLOS ONE from Public Library of Science
Bibliographic data for series maintained by plosone ().