Field Evaluation of PIMA Point-of-Care CD4 Testing in Rakai, Uganda

Ronald M Galiwango, Lawrence Lubyayi, Richard Musoke, Sarah Kalibbala, Martin Buwembo, Jjingo Kasule, David Serwadda, Ronald H Gray, Steven J Reynolds and Larry W Chang

PLOS ONE, 2014, vol. 9, issue 3, 1-5

Abstract: Objective: To assess the accuracy of PIMA Point-of-Care (POC) CD4 testing in rural Rakai, Uganda. Methods: 903 HIV positive persons attending field clinics provided a venous blood sample assessed on site using PIMA analyzers per manufacturer's specifications. The venous samples were then run on FACSCalibur flow cytometry at a central facility. The Bland–Altman method was used to estimate mean bias and 95% limits of agreement (LOA). Sensitivity, specificity, negative predictive value (NPV), and positive predictive value (PPV) were calculated for a CD4 threshold of

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0088928

DOI: 10.1371/journal.pone.0088928

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