FDA’s Nozzle Numerical Simulation Challenge: Non-Newtonian Fluid Effects and Blood Damage

Miquel Trias, Antonio Arbona, Joan Massó, Borja Miñano and Carles Bona

PLOS ONE, 2014, vol. 9, issue 3, 1-14

Abstract: Data from FDA’s nozzle challenge–a study to assess the suitability of simulating fluid flow in an idealized medical device–is used to validate the simulations obtained from a numerical, finite-differences code. Various physiological indicators are computed and compared with experimental data from three different laboratories, getting a very good agreement. Special care is taken with the derivation of blood damage (hemolysis). The paper is focused on the laminar regime, in order to investigate non-Newtonian effects (non-constant fluid viscosity). The code can deal with these effects with just a small extra computational cost, improving Newtonian estimations up to a ten percent. The relevance of non-Newtonian effects for hemolysis parameters is discussed.

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0092638

DOI: 10.1371/journal.pone.0092638

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