Mortality and Case Fatality Due to Visceral Leishmaniasis in Brazil: A Nationwide Analysis of Epidemiology, Trends and Spatial Patterns

Francisco Rogerlândio Martins-Melo, Mauricélia da Silveira Lima, Alberto Novaes Ramos, Carlos Henrique Alencar and Jorg Heukelbach

PLOS ONE, 2014, vol. 9, issue 4, 1-14

Abstract: Background: Visceral leishmaniasis (VL) is a significant public health problem in Brazil and several regions of the world. This study investigated the magnitude, temporal trends and spatial distribution of mortality related to VL in Brazil. Methods: We performed a study based on secondary data obtained from the Brazilian Mortality Information System. We included all deaths in Brazil from 2000 to 2011, in which VL was recorded as cause of death. We present epidemiological characteristics, trend analysis of mortality and case fatality rates by joinpoint regression models, and spatial analysis using municipalities as geographical units of analysis. Results: In the study period, 12,491,280 deaths were recorded in Brazil. VL was mentioned in 3,322 (0.03%) deaths. Average annual age-adjusted mortality rate was 0.15 deaths per 100,000 inhabitants and case fatality rate 8.1%. Highest mortality rates were observed in males (0.19 deaths/100,000 inhabitants),

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0093770

DOI: 10.1371/journal.pone.0093770

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