Cardio-Respiratory Coordination Increases during Sleep Apnea

Maik Riedl, Andreas Müller, Jan F Kraemer, Thomas Penzel, Juergen Kurths and Niels Wessel

PLOS ONE, 2014, vol. 9, issue 4, 1-7

Abstract: Cardiovascular diseases are the main source of morbidity and mortality in the United States with costs of more than $170 billion. Repetitive respiratory disorders during sleep are assumed to be a major cause of these diseases. Therefore, the understanding of the cardio-respiratory regulation during these events is of high public interest. One of the governing mechanisms is the mutual influence of the cardiac and respiratory oscillations on their respective onsets, the cardio-respiratory coordination (CRC). We analyze this mechanism based on nocturnal measurements of 27 males suffering from obstructive sleep apnea syndrome. Here we find, by using an advanced analysis technique, the coordigram, not only that the occurrence of CRC is significantly more frequent during respiratory sleep disturbances than in normal respiration (p-value

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0093866

DOI: 10.1371/journal.pone.0093866

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