Association of rs6265 and rs2030324 Polymorphisms in Brain-Derived Neurotrophic Factor Gene with Alzheimer’s Disease: A Meta-Analysis

Yan Lin, Shuo Cheng, Zhutian Xie and Dongfeng Zhang

PLOS ONE, 2014, vol. 9, issue 4, 1-12

Abstract: Background: The association between polymorphisms rs6265 and rs2030324 in brain-derived neurotrophic factor (BDNF) and Alzheimer’s disease (AD) has been widely reported, but the results remain controversial. Methods: A comprehensive search of Pubmed, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang Med Online and China Biology Medical literature database (CBM) was performed. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using fixed or random-effects models. We excluded the studies with OR>3.0 or OR

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0094961

DOI: 10.1371/journal.pone.0094961

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