Prognostic Value of PLR in Various Cancers: A Meta-Analysis

Xin Zhou, Yiping Du, Zebo Huang, Jun Xu, Tianzhu Qiu, Jian Wang, Tongshan Wang, Wei Zhu and Ping Liu

PLOS ONE, 2014, vol. 9, issue 6, 1-8

Abstract: Background: Recently, more and more studies investigated the association of inflammation parameters such as the Platelet Lymphocyte Ratio (PLR) and the prognosis of various cancers. However, the prognostic role of PLR in cancer remains controversial. Methods: We conducted a meta-analysis of published studies to evaluate the prognostic value of PLR in various cancers. In order to investigate the association between PLR and overall survival (OS), the hazard ratio (HR) and its 95% confidence interval (CI) were calculated. Results: A total of 13964 patients from 26 studies were included in the analysis. The summary results showed that elevated PLR was a negative predictor for OS with HR of 1.60 (95%CI: 1.35–1.90; Pheterogeneity

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0101119

DOI: 10.1371/journal.pone.0101119

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