Inter-Vendor Reproducibility of Pseudo-Continuous Arterial Spin Labeling at 3 Tesla

Henri J M M Mutsaerts, Rebecca M E Steketee, Dennis F R Heijtel, Joost P A Kuijer, Matthias J P van Osch, Charles B L M Majoie, Marion Smits and Aart J Nederveen

PLOS ONE, 2014, vol. 9, issue 8, 1-10

Abstract: Purpose: Prior to the implementation of arterial spin labeling (ASL) in clinical multi-center studies, it is important to establish its status quo inter-vendor reproducibility. This study evaluates and compares the intra- and inter-vendor reproducibility of pseudo-continuous ASL (pCASL) as clinically implemented by GE and Philips. Material and Methods: 22 healthy volunteers were scanned twice on both a 3T GE and a 3T Philips scanner. The main difference in implementation between the vendors was the readout module: spiral 3D fast spin echo vs. 2D gradient-echo echo-planar imaging respectively. Mean and variation of cerebral blood flow (CBF) were compared for the total gray matter (GM) and white matter (WM), and on a voxel-level. Results: Whereas the mean GM CBF of both vendors was almost equal (p = 1.0), the mean WM CBF was significantly different (p

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0104108

DOI: 10.1371/journal.pone.0104108

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