Seroprevalence of Merkel Cell Polyomavirus in the General Rural Population of Anyang, China

Chanyuan Zhang, Fangfang Liu, Zhonghu He, Qiuju Deng, Yaqi Pan, Ying Liu, Chaoting Zhang, Tao Ning, Chuanhai Guo, Yongmei Liang, Ruiping Xu, Lixin Zhang, Hong Cai and Yang Ke

PLOS ONE, 2014, vol. 9, issue 9, 1-8

Abstract: Background: Despite the probably causal link between Merkel cell polyomavirus (MCPyV) infection and Merkel cell carcinoma (MCC), a rare but aggressive skin malignancy, little is known about the seroepidemiology of MCPyV among healthy adults in China. Methods: Serum antibodies against MCPyV were evaluated by multiplex serology in a population-based study of 5548 adults (including 1587 heterosexual couples) aged 25–65 years who were enrolled from rural Anyang, China in 2007–2009. Univariate and multivariate logistic regression analyses were performed to assess the risk factors for the seropositivity of MCPyV. Results: The seroprevalence for MCPyV was 61.0%. MCPyV seropositivity was significantly higher in males than in females (64.5% vs. 57.7%, P

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0106430

DOI: 10.1371/journal.pone.0106430

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