Association of Common Variants in TCF4 and PTPRG with Fuchs' Corneal Dystrophy: A Systematic Review and Meta-Analysis

Lawrence C M Lau, Li Ma, Alvin L Young, Shi Song Rong, Vishal Jhanji, Marten E Brelen, Chi Pui Pang and Li Jia Chen

PLOS ONE, 2014, vol. 9, issue 10, 1-8

Abstract: Topic: A meta-analysis of TCF4 and PTPRG gene variants in Fuchs' corneal dystrophy (FCD). Clinical relevance: To identify novel genetic markers in patients with FCD in different ethnic populations. Methods: MEDLINE and EMBASE were searched for eligible genetic studies on TCF4 and PTPRG in FCD. Odds ratios (OR) and 95% confidence intervals (CI) of each single-nucleotide polymorphism (SNP) in allelic, dominant and recessive models were estimated using fixed-effect model if I2

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0109142

DOI: 10.1371/journal.pone.0109142

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