Multisite Evaluation of Point of Care CD4 Testing in Papua New Guinea

Malin Malagun, Gideon Nano, Caroline Chevallier, Ragagalo Opina, Gola Sawiya, Joseph Kivavia, Albina Kalinoe, Kathalina Nathaniel, Oscillah Kaminiel, John Millan, Andrea Carmone, Mary Dini, Theresa Palou, Kum Topma, Evelyn Lavu and Jessica Markby

PLOS ONE, 2014, vol. 9, issue 11, 1-15

Abstract: Laboratory-based CD4 monitoring of HIV patients presents challenges in resource limited settings (RLS) including frequent machine breakdown, poor engineering support and limited cold chain and specimen transport logistics. This study assessed the performance of two CD4 tests designed for use in RLS; the Dynal assay and the Alere PIMA test (PIMA). Accuracy of Dynal and PIMA using venous blood was assessed in a centralised laboratory by comparison to BD FACSCount (BD FACS). Dynal had a mean bias of −50.35 cells/µl (r2 = 0.973, p

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0112173

DOI: 10.1371/journal.pone.0112173

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