Clinical Features and Risk Factors for Atazanavir (ATV)-Associated Urolithiasis: A Case-Control Study

Matthieu Lafaurie, Barbara De Sousa, Diane Ponscarme, Nathanael Lapidus, Michel Daudon, Laurence Weiss, Christophe Rioux, Erwan Fourn, Christine Katlama and Jean-Michel Molina

PLOS ONE, 2014, vol. 9, issue 11, 1-5

Abstract: Objectives: Clinical features and risk factors for atazanavir (ATV)-associated urolithiasis have not been fully investigated. Methods: We reviewed all cases of ATV-containing urolithiasis identified by infrared spectrophotometry among HIV-infected patients over a 5-year period to describe their clinical features and outcome. A case-control study was performed to identify risk factors associated with ATV-associated urolithiasis using univariate and multivariate logistic regression analyses. Results: 30 cases of ATV-associated urolithiasis were analyzed. Patients were mostly men (87%), median age: 45.5 years, median CD4 cell count: 443 cells/µL and 97% had plasma HIV RNA level

Date: 2014
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0112836

DOI: 10.1371/journal.pone.0112836

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