Factors Affecting Cerebral Oxygenation in Hemodialysis Patients: Cerebral Oxygenation Associates with pH, Hemodialysis Duration, Serum Albumin Concentration, and Diabetes Mellitus

Kiyonori Ito, Susumu Ookawara, Yuichiro Ueda, Sawako Goto, Haruhisa Miyazawa, Hodaka Yamada, Taisuke Kitano, Mitsunobu Shindo, Yoshio Kaku, Keiji Hirai, Masashi Yoshida, Taro Hoshino, Aoi Nabata, Honami Mori, Izumi Yoshida, Masafumi Kakei and Kaoru Tabei

PLOS ONE, 2015, vol. 10, issue 2, 1-11

Abstract: Background: Patients undergoing hemodialysis (HD) often develop cerebral disease complications. Furthermore, cerebral regional saturation of oxygen (rSO2) was previously reported to be significantly lower in HD patients than in healthy subjects. We aimed to identify the factors affecting the cerebral rSO2 in HD patients. Methods: Fifty-four HD patients (38 men and 16 women; mean age, 67.7 ± 1.2 years, HD duration, 6.5 ± 1.9 years) were recruited. Cerebral rSO2 was monitored at the forehead before HD using an INVOS 5100C (Covidien Japan, Tokyo, Japan). Results: The rSO2 levels were significantly lower in HD patients compared with healthy controls (49.5 ± 1.7% vs. 68.9 ± 1.6%, p

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0117474

DOI: 10.1371/journal.pone.0117474

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