Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass-Spectrometry (MALDI-TOF MS) Based Typing of Extended-Spectrum β-Lactamase Producing E. coli – A Novel Tool for Real-Time Outbreak Investigation

Adrian Egli, Sarah Tschudin-Sutter, Michael Oberle, Daniel Goldenberger, Reno Frei and Andreas F Widmer

PLOS ONE, 2015, vol. 10, issue 4, 1-6

Abstract: Epidemiologically linked clusters are confirmed by typing strains with molecular typing such as pulsed-field gel electrophoresis (PFGE). We compared six extended-spectrum β-lactamase producing E. coli of a PFGE-related cluster with Matrix-assisted laser desorption/ionization-time of flight mass-spectrometry based typing that confirmed relatedness faster and more cost-effective, but as reliable as PFGE.

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0120624

DOI: 10.1371/journal.pone.0120624

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