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Association between Childhood Strabismus and Refractive Error in Chinese Preschool Children

Hui Zhu, Jia-Jia Yu, Rong-Bin Yu, Hui Ding, Jing Bai, Ji Chen and Hu Liu

PLOS ONE, 2015, vol. 10, issue 3, 1-11

Abstract: Purpose: To investigate the association between concomitant esotropia or concomitant exotropia and refractive error in preschool children Methods: A population-based sample of 5831 children aged 3 to 6 years was selected from all kindergartens in a representative county (Yuhuatai District, Nanjing, Jiangsu Province) of Nanjing, China. Clinical examinations including ocular alignment, ocular motility, visual acuity, optometry, stereopsis screening, slit lamp examination and fundus examination were performed by trained ophthalmologists and optometrists. Odd ratios (OR) and 95% confidence intervals (95% CI) were calculated to evaluate the association of refractive error with concomitant esotropia and concomitant exotropia. Results: In multivariate logistic regression analysis, concomitant esotropia was associated independently with spherical equivalent anisometropia (OR, 3.15 for 0.50 to = 1.00 D of anisometropia) and hyperopia. There was a severity-dependent association of hyperopia with the development of concomitant esotropia, with ORs increasing from 9.3 for 2.00 to = 5.00 D of hyperopia. Concomitant exotropia was associated with astigmatism (OR, 3.56 for 0.50 to 1.00 D of astigmatism, and 1.9 for

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0120720

DOI: 10.1371/journal.pone.0120720

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