Limitations of Stroke Volume Estimation by Non-Invasive Blood Pressure Monitoring in Hypergravity

Olivier Manen, Caroline Dussault, Fabien Sauvet and Stéphanie Montmerle-Borgdorff

PLOS ONE, 2015, vol. 10, issue 3, 1-13

Abstract: Background: Altitude and gravity changes during aeromedical evacuations induce exacerbated cardiovascular responses in unstable patients. Non-invasive cardiac output monitoring is difficult to perform in this environment with limited access to the patient. We evaluated the feasibility and accuracy of stroke volume estimation by finger photoplethysmography (SVp) in hypergravity. Methods: Finger arterial blood pressure (ABP) waveforms were recorded continuously in ten healthy subjects before, during and after exposure to +Gz accelerations in a human centrifuge. The protocol consisted of a 2-min and 8-min exposure up to +4 Gz. SVp was computed from ABP using Liljestrand, systolic area, and Windkessel algorithms, and compared with reference values measured by echocardiography (SVe) before and after the centrifuge runs. Results: The ABP signal could be used in 83.3% of cases. After calibration with echocardiography, SVp changes did not differ from SVe and values were linearly correlated (p

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0121936

DOI: 10.1371/journal.pone.0121936

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