Circumpapillary Course of Retinal Pigment Epithelium Can Be Fit to Sine Wave and Amplitude of Sine Wave Is Significantly Correlated with Ovality Ratio of Optic Disc

Takehiro Yamashita, Taiji Sakamoto, Naoya Yoshihara, Hiroto Terasaki, Yuya Kii, Minoru Tanaka and Kumiko Nakao

PLOS ONE, 2015, vol. 10, issue 4, 1-10

Abstract: The purpose of this study was to develop a method of quantifying the degree of optic disc tilt in normal eyes. This was a prospective, observational cross sectional study of 126 right eyes of 126 healthy volunteers. The optic disc tilt was determined from the circular peripapillary optical coherence tomographic (OCT) scan images. The course of the retinal pigment epithelium (RPE) layer in the peripapillary cross sectional scan images was fit to a sine wave curve, and the amplitude of the sine curve was used to reflect the degree of the optic disc tilt in the optical axis. The repeatability of the amplitude determinations was calculated. The correlation between the amplitude and the ovality ratio of the optic disc was determined. The correlation between the amplitude and the body height was also calculated. The mean amplitudewas 36.6 ± 17.5 pixels, which was significantly and inversely correlated with the ovality ratio of the optic disc (R = -0.59, P

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0122191

DOI: 10.1371/journal.pone.0122191

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