Adjunctive Medical Therapy with α-Blocker after Extracorporeal Shock Wave Lithotripsy of Renal and Ureteral Stones: A Meta-Analysis

Mingchao Li, Zhengyun Wang, Jun Yang, Xiaolin Guo, Tao Wang, Shaogang Wang, Chunping Yin, Jihong Liu and Zhangqun Ye

PLOS ONE, 2015, vol. 10, issue 4, 1-18

Abstract: Background: Although some trials assessed the efficacy and safety of the α-blocker in facilitating renal and ureteral stones expulsion after extracorporeal shock wave lithotripsy (ESWL), the role of the α-blocker in facilitating upper urinary calculi expulsion after ESWL remain controversial. Aims: To determine the efficacy and safety of the α-blocker in facilitating renal and ureteral stones expulsion after ESWL. Methods: A literature search was carried out using the PubMed database, EMBASE and the Cochrane Library database to identify relevant studies. Two reviewers independently extracted data and assessed methodological quality. Pooled effect estimates were obtained using a fixed- and random-effects meta-analysis. Results: The meta-analysis included 23 RCTs, α-blocker significantly enhanced expulsion rate of upper urinary tract calculi after ESWL (P

Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:plo:pone00:0122497

DOI: 10.1371/journal.pone.0122497

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